5-bromo-2,3-dimethoxypyrazine
$300.00
CAS No.: 89466-19-3
Catalog No.: 196344
Purity: 95%
MF: C6H7BrN2O2
MW: 219.038
Storage: 2-8 degree Celsius
SMILES: BrC=1N=C(C(=NC1)OC)OC
Catalog No.: 196344
Purity: 95%
MF: C6H7BrN2O2
MW: 219.038
Storage: 2-8 degree Celsius
SMILES: BrC=1N=C(C(=NC1)OC)OC
5-bromo-2,3-dimethoxypyrazine; CAS No.: 89466-19-3; 5-bromo-2,3-dimethoxypyrazine. PROPERTIES: This compound features a 5-bromo-2,3-dimethoxypyrazine structure, combining a bromine atom and two methoxy substituents on the pyrazine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 221.0 g/mol (C5H5BrN2O2). The melting point ranges between 100-105 C, and it exhibits moderate solubility in common organic solvents like DMSO and DMF while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 5-Bromo-2,3-dimethoxypyrazine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 5-bromo-2,3-dimethoxypyrazine structure allows for participation in various reactions, including palladium-catalyzed cross-coupling reactions at the bromine position and nucleophilic substitution at the pyrazine ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The bromine atom provides a handle for introducing aryl, vinyl, or heterocyclic substituents. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel bromodimethoxypyrazine derivatives based on the 5-bromo-2,3-dimethoxypyrazine scaffold.
Reviews
Write Your Own Review