5-chloropyrazine-2-carbohydrazide
$250.00
CAS No.: 848952-83-0
Catalog No.: 196335
Purity: 95%
MF: C5H5ClN4O
MW: 172.575
Storage: 2-8 degree Celsius
SMILES: ClC=1N=CC(=NC1)C(=O)NN
Catalog No.: 196335
Purity: 95%
MF: C5H5ClN4O
MW: 172.575
Storage: 2-8 degree Celsius
SMILES: ClC=1N=CC(=NC1)C(=O)NN
5-chloropyrazine-2-carbohydrazide; CAS No.: 848952-83-0; 5-chloropyrazine-2-carbohydrazide. PROPERTIES: This compound features a 5-chloropyrazine-2-carbohydrazide structure, combining a chloro substituent and a carbohydrazide group on the pyrazine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 185.0 g/mol (C5H6ClN5O). The melting point ranges between 190-195 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 5-Chloropyrazine-2-carbohydrazide serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 5-chloropyrazine-2-carbohydrazide structure allows for participation in various reactions, including nucleophilic substitution at the pyrazine ring and condensation reactions to form hydrazones. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The chloro substituent provides a handle for introducing aryl, vinyl, or heterocyclic substituents. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel chloropyrazine derivatives based on the 5-chloropyrazine-2-carbohydrazide scaffold.
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