3-Ethoxypyrazin-2-amine
$300.00
CAS No.: 89464-86-8
Catalog No.: 196332
Purity: 95%
MF: C6H9N3O
MW: 139.158
Storage: 2-8 degree Celsius
SMILES: C(C)OC=1C(=NC=CN1)N
Catalog No.: 196332
Purity: 95%
MF: C6H9N3O
MW: 139.158
Storage: 2-8 degree Celsius
SMILES: C(C)OC=1C(=NC=CN1)N
3-Ethoxypyrazin-2-amine; CAS No.: 89464-86-8; 3-Ethoxypyrazin-2-amine. PROPERTIES: This compound features a 3-ethoxypyrazin-2-amine structure, combining an ethoxy group and an amine group on the pyrazine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 152.1 g/mol (C6H10N3O). The melting point ranges between 90-95 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 3-Ethoxypyrazin-2-amine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 3-ethoxypyrazin-2-amine structure allows for participation in various reactions, including nucleophilic substitution at the pyrazine ring and hydrogen bonding interactions through the ethoxy group. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The ethoxy group provides steric and electronic effects that influence binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel ethoxypyrazine derivatives based on the 3-ethoxypyrazin-2-amine scaffold.
Reviews
Write Your Own Review