(2-morpholinophenyl)methanol

(2-morpholinophenyl)methanol

4-(4-nitrobenzyl)morpholine

4-(4-nitrobenzyl)morpholine

(4-morpholinophenyl)methanol

$200.00
CAS No.: 280556-71-0
Catalog No.: 196256
Purity: 95%
MF: C11H15NO2
MW: 193.246
Storage: 2-8 degree Celsius
SMILES: O1CCN(CC1)C1=CC=C(C=C1)CO
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196256
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(4-morpholinophenyl)methanol; CAS No.: 280556-71-0; (4-morpholinophenyl)methanol. PROPERTIES: This compound features a (4-morpholinophenyl)methanol structure, combining a morpholine group, a phenyl ring, and a hydroxymethyl substituent. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 191.2 g/mol (C11H15NO2). The melting point ranges between 50-55 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: (4-Morpholinophenyl)methanol serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its (4-morpholinophenyl)methanol structure enables diverse reactivity patterns, including nucleophilic substitution at the hydroxymethyl group and hydrogen bonding interactions through the morpholine nitrogen. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The morpholine group provides hydrogen-bonding capabilities for improved target binding. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel morpholinophenyl derivatives based on the (4-morpholinophenyl)methanol scaffold.

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