(2-morpholinophenyl)methanol
$300.00
CAS No.: 465514-33-4
Catalog No.: 196255
Purity: 95%
MF: C11H15NO2
MW: 193.246
Storage: 2-8 degree Celsius
SMILES: O1CCN(CC1)C1=C(C=CC=C1)CO
Catalog No.: 196255
Purity: 95%
MF: C11H15NO2
MW: 193.246
Storage: 2-8 degree Celsius
SMILES: O1CCN(CC1)C1=C(C=CC=C1)CO
(2-morpholinophenyl)methanol; CAS No.: 465514-33-4; (2-morpholinophenyl)methanol. PROPERTIES: This compound presents a (2-morpholinophenyl)methanol structure, combining a morpholine group, a phenyl ring, and a hydroxymethyl substituent. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 191.2 g/mol (C11H15NO2). The melting point ranges between 50-55 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: (2-Morpholinophenyl)methanol serves as a specialized intermediate in pharmaceutical research. Its (2-morpholinophenyl)methanol structure enables diverse reactivity patterns, including nucleophilic substitution at the hydroxymethyl group and hydrogen bonding interactions through the morpholine nitrogen. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The morpholine group provides hydrogen-bonding capabilities for improved target binding. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the (2-morpholinophenyl)methanol scaffold for improved biological activity and pharmacokinetic properties.
Reviews
Write Your Own Review