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8-fluoroisoquinoline-1-carboxylic acid; CAS No.: 1780197-11-6; 8-fluoroisoquinoline-1-carboxylic acid. PROPERTIES: 8-fluoroisoquinoline-1-carboxylic acid appears as a white crystalline powder with molecular formula C9H5FNO2. It has a melting point of approximately 200-205 C and exhibits limited aqueous solubility but good solubility in DMSO and DMF. Proper storage requires a tightly sealed container in a cool, dry place (ideally 15-25 C). Safety precautions include wearing protective gloves and eye protection as this compound may cause skin and eye irritation. APPLICATIONS: This fluorinated isoquinoline carboxylic acid is utilized in the development of antimicrobial agents. The fluorine substituent enhances bioavailability while the carboxylic acid group forms critical interactions with bacterial targets as reported in pharmaceutical chemistry journals. In materials science, 8-fluoroisoquinoline-1-carboxylic acid derivatives have found application in creating electron-transport materials for organic light-emitting diodes. According to materials chemistry research, the electron-withdrawing fluorine group improves charge transport properties while the isoquinoline scaffold provides structural rigidity.