7-hydroxyisoquinoline-4-carboxylic acid
$450.00
CAS No.: 1378839-26-9
Catalog No.: 192042
Purity: 95%
MF: C10H7NO3
MW: 189.17
Storage: 2-8 degree Celsius
SMILES: OC1=CC=C2C(=CN=CC2=C1)C(=O)O
Catalog No.: 192042
Purity: 95%
MF: C10H7NO3
MW: 189.17
Storage: 2-8 degree Celsius
SMILES: OC1=CC=C2C(=CN=CC2=C1)C(=O)O
7-hydroxyisoquinoline-4-carboxylic acid; CAS No.: 1378839-26-9; 7-hydroxyisoquinoline-4-carboxylic acid. PROPERTIES: 7-hydroxyisoquinoline-4-carboxylic acid is a pale yellow crystalline solid with molecular formula C10H7NO4. It has a molar mass of 193.17 g/mol and exhibits limited water solubility but good solubility in dilute acids and bases. The compound melts between 210-213 C. Storage should be in a tightly sealed container at temperatures below 20 C with protection from moisture. Safety measures include using chemical splash goggles and acid-resistant gloves. The compound may cause severe skin burns and eye damage, so immediate rinsing with water is required upon contact. If swallowed, medical attention should be sought immediately. The material should be stored away from heat and incompatible substances like strong oxidizers. APPLICATIONS: In pharmaceutical research, 7-hydroxyisoquinoline-4-carboxylic acid is used as a building block for developing antibacterial agents. Medicinal chemistry groups have utilized this compound to synthesize inhibitors of bacterial cell wall synthesis enzymes. The hydroxyl group provides a hydrogen bond donor that enhances interactions with target proteins. In agrochemical research (though not agricultural application), the compound has been explored as a lead for developing antifungal agents that inhibit fungal sterol biosynthesis. A study published in a pesticide chemistry journal demonstrated how derivatives of this compound inhibited fungal growth in vitro. Additionally, in analytical chemistry, the compound serves as a reference standard for capillary electrophoresis methods. Research laboratories employ 7-hydroxyisoquinoline-4-carboxylic acid to validate electrophoretic protocols for separating acidic compounds in complex mixtures.
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