7-fluoroisoquinolin-4-amine
$400.00
CAS No.: 1785090-95-0
Catalog No.: 191986
Purity: 95%
MF: C9H7FN2
MW: 162.167
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C2C(=CN=CC2=C1)N
Catalog No.: 191986
Purity: 95%
MF: C9H7FN2
MW: 162.167
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C2C(=CN=CC2=C1)N
7-fluoroisoquinolin-4-amine; CAS No.: 1785090-95-0;7-fluoroisoquinolin-4-amine. PROPERTIES: 7-fluoroisoquinolin-4-amine is a halogenated heterocyclic amine with molecular formula C9H6FNN2. This crystalline solid typically exhibits a pale yellow color and has a melting point ranging between 165-170 C. The compound demonstrates moderate solubility in polar organic solvents like methanol and dichloromethane while being sparingly soluble in water. The 7-fluoroisoquinolin-4-amine structure contains a highly reactive amine group positioned para to the fluorine substituent on the isoquinoline ring system. Proper storage requires a tightly sealed container in a desiccator with appropriate drying agents, maintained at temperatures below 5 C to prevent hydrolytic degradation. Safety precautions include using P290 respiratory protection and Nitrile gloves during handling, as the compound may cause respiratory irritation and skin sensitization. According to EU safety regulations, it carries H317 and H335 hazard statements for potential sensitization and respiratory tract irritation. APPLICATIONS: The 7-fluoroisoquinolin-4-amine molecule serves as a key intermediate in the synthesis of isoquinoline-based antimicrobial agents, as reported in medicinal chemistry research focusing on antibiotic development. The fluorine substitution enhances metabolic stability while the amine group provides a site for further functionalization via reductive alkylation. Additionally, 7-fluoroisoquinolin-4-amine derivatives have been investigated for their fluorescent properties in chemical sensing applications, as described in analytical chemistry literature. The compound's ability to participate in hydrogen bonding interactions has also made it valuable in designing molecules with optimized bioavailability, as discussed in pharmaceutical formulation studies emphasizing drug delivery systems.
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