3,3-dimethylindolin-4-amine dihydrochloride
$400.00
CAS No.: 2411639-80-8
Catalog No.: 192696
Purity: 95%
MF: C10H16Cl2N2
MW: 235.158
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.CC1(CNC=2C=CC=C(C12)N)C
Catalog No.: 192696
Purity: 95%
MF: C10H16Cl2N2
MW: 235.158
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.CC1(CNC=2C=CC=C(C12)N)C
3,3-dimethylindolin-4-amine dihydrochloride; CAS No.: 2411639-80-8; 3,3-dimethylindolin-4-amine dihydrochloride. PROPERTIES: This dimethylated indoline amine salt has molecular formula C9H13N2 {2HCl. It generally appears as a white crystalline powder. The 3,3-dimethylindolin-4-amine dihydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 220-225 C (with decomposition), and it has a molecular weight of approximately 209.12 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The dihydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 3,3-dimethylindolin-4-amine dihydrochloride serves as a critical intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the dimethyl groups enhance metabolic stability and the amine group provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The amine group can be further functionalized through alkylation or acylation reactions to produce various derivatives for chemical research applications.
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