4-Iodo-1H-indole
$250.00
CAS No.: 81038-38-2
Catalog No.: 195551
Purity: 95%
MF: C8H6IN
MW: 243.047
Storage: 2-8 degree Celsius
SMILES: IC1=C2C=CNC2=CC=C1
Catalog No.: 195551
Purity: 95%
MF: C8H6IN
MW: 243.047
Storage: 2-8 degree Celsius
SMILES: IC1=C2C=CNC2=CC=C1
4-Iodo-1H-indole; CAS No.: 81038-38-2; 4-Iodo-1H-indole. PROPERTIES: 4-Iodo-1H-indole is a dark brown crystalline solid with molecular formula C8H6IN. It exhibits a melting point around 100-103 C and moderate thermal stability. The compound shows limited solubility in common organic solvents but can be dissolved in hot DMSO. Recommended storage conditions include maintaining temperatures below 25 C in sealed containers. Safety considerations involve using iodine-specific waste containers for disposal and avoiding contact with reducing agents due to potential redox reactions. APPLICATIONS: This iodinated indole serves as a key building block in the synthesis of serotonin receptor ligands, where the 4-iodo-1H-indole group facilitates receptor subtype selectivity (Journal of Medicinal Chemistry). In materials science, the compound is incorporated into organic light-emitting diodes (OLEDs) as a blue-emitting material due to its electronic structure (Advanced Materials). Furthermore, its iodine substituent enables convenient cross-coupling reactions for the preparation of biaryl-containing libraries used in high-throughput screening campaigns (Angewandte Chemie International Edition).
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