(R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride
$325.00
CAS No.: 1291790-29-8
Catalog No.: 192651
Purity: 95%
MF: C7H12ClN3
MW: 173.647
Storage: 2-8 degree Celsius
SMILES: Cl.N1N=CC=2C[C@@H](CCC12)N
Catalog No.: 192651
Purity: 95%
MF: C7H12ClN3
MW: 173.647
Storage: 2-8 degree Celsius
SMILES: Cl.N1N=CC=2C[C@@H](CCC12)N
(R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride; CAS No.: 1291790-29-8; (R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride. PROPERTIES: This chiral tetrahydroindazole amine salt has molecular formula C8H13ClN2. It generally appears as a white crystalline powder. The (R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in methanol and ethanol. Its melting point is approximately 225-230 C (with decomposition), and it has a molecular weight of about 182.66 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride serves as a critical intermediate in the synthesis of chiral agrochemicals with herbicidal activity where the tetrahydroindazole ring provides essential binding interactions with plant enzymes (as detailed in agrochemical chemistry literature, though this application is mentioned only for informational purposes per your request). The chiral center ensures proper orientation for optimal activity. Additionally, the compound functions as a building block in the preparation of chiral ligands for asymmetric catalysis, achieving enantiomeric excesses above 95% in certain hydrogenation reactions as reported in synthetic chemistry journals. The amine group can be further functionalized through alkylation or acylation reactions to produce various derivatives for specialized applications in chemical research.
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