1-(1H-indazol-4-yl)ethan-1-amine
$250.00
CAS No.: 1159511-31-5
Catalog No.: 192650
Purity: 95%
MF: C9H11N3
MW: 161.208
Storage: 2-8 degree Celsius
SMILES: N1N=CC2=C(C=CC=C12)C(C)N
Catalog No.: 192650
Purity: 95%
MF: C9H11N3
MW: 161.208
Storage: 2-8 degree Celsius
SMILES: N1N=CC2=C(C=CC=C12)C(C)N
1-(1H-indazol-4-yl)ethan-1-amine; CAS No.: 1159511-31-5; 1-(1H-indazol-4-yl)ethan-1-amine. PROPERTIES: This indazole-substituted ethylamine has molecular formula C9H11N3. It typically appears as a colorless to pale yellow oil. The 1-(1H-indazol-4-yl)ethan-1-amine demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate but limited water solubility. Its boiling point ranges between 185-190 C at 760 mmHg, and it has a molecular weight of approximately 157.2 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong oxidizing agents and may form explosive peroxides upon prolonged exposure to air. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 1-(1H-indazol-4-yl)ethan-1-amine functions as a key intermediate in the synthesis of dopamine D3 receptor antagonists for neurological disorders where the ethylamine group provides essential amine functionality for receptor interaction (as reported in medicinal chemistry literature). The indazole ring system provides planar aromatic interactions important for binding affinity. Additionally, the compound serves as a building block in the preparation of fluorescent dyes for bioimaging applications with excitation maxima around 350 nm and emission maxima around 420 nm, as described in bioanalytical chemistry journals. The amine group can be further functionalized through acylation or sulfonamidation reactions to produce various derivatives for chemical research applications.
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