5-fluoro-3-iodo-1H-indazole
$400.00
CAS No.: 858629-06-8
Catalog No.: 111060
Purity: 95%
MF: C7H4FIN2
MW: 262.025
Storage: 2-8 degree Celsius
SMILES: FC1=CC2=C(NN=C2I)C=C1
Catalog No.: 111060
Purity: 95%
MF: C7H4FIN2
MW: 262.025
Storage: 2-8 degree Celsius
SMILES: FC1=CC2=C(NN=C2I)C=C1
5-fluoro-3-iodo-1H-indazole; CAS No.: 858629-06-8; ChemShuttle supplies halogen-rich screening compounds like 5-fluoro-3-iodo-1H-indazole, designed for fragment-based drug discovery. The strategic placement of halogen atoms (ortho-fluoro and meta-iodo) creates unique electronic effects and halogen bonding potential. With molecular weight 266.97 and XLogP3 2.8, this compound fits lead-like property space for kinase inhibition. Our CRO chemical synthesis team developed a regioselective iodination protocol using NIS in TFA, achieving >95% purity. The iodine atom serves as an excellent handle for subsequent cross-coupling reactions while the fluorine enhances bioavailability. We provide crystallography-grade material with polymorph screening data to support structure-based drug design initiatives.
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