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6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine
$300.00
CAS No.: 1262619-64-6
Catalog No.: 195528
Purity: 95%
MF: C8H4BrF3N2
MW: 265.032
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC=2N(C1)C(=NC2)C(F)(F)F
Catalog No.: 195528
Purity: 95%
MF: C8H4BrF3N2
MW: 265.032
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC=2N(C1)C(=NC2)C(F)(F)F
6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine; CAS No.: 1262619-64-6; 6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine. PROPERTIES: 6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine is a high-melting crystalline compound with molecular formula C9H5BrF3N2. It demonstrates a melting point exceeding 220 C and exhibits excellent thermal stability. The compound shows low solubility in common organic solvents but can be dissolved in hot DMF or DMSO. Proper storage requires keeping it in sealed containers at room temperature away from direct sunlight. Safety considerations include handling under inert atmosphere when moisture sensitivity is suspected and employing standard laboratory safety equipment to prevent bromine and fluorine-containing vapors from causing respiratory issues. APPLICATIONS: This brominated heterocycle serves as a potent building block in targeted cancer therapy research, particularly in the development of PARP inhibitors where the 6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine moiety enhances target binding affinity (Cancer Research). In materials science, its electron-withdrawing substituents make it suitable for incorporation into organic semiconductors used in thin-film transistors (Journal of Materials Chemistry C). Additionally, the compound's bromine substituent enables convenient cross-coupling reactions for the synthesis of structurally diverse libraries in medicinal chemistry campaigns (Angewandte Chemie International Edition).
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