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methyl 7-chloroimidazo[1,5-a]pyridine-5-carboxylate; CAS No.: 1427448-43-8; methyl 7-chloroimidazo[1,5-a]pyridine-5-carboxylate. PROPERTIES: Methyl 7-chloroimidazo[1,5-a]pyridine-5-carboxylate presents as a pale yellow crystalline solid with molecular weight 223.65 g/mol. It exhibits a melting point of approximately 189-192 C and moderate thermal stability up to 200 C. The compound shows good solubility in polar aprotic solvents like acetone and ethyl acetate but limited water solubility. Recommended storage conditions include maintaining temperatures below 25 C in amber glass containers protected from light. Safety measures require handling in well-ventilated areas with personal protective equipment to avoid exposure to eyes and skin, as the chloro group may cause irritation. APPLICATIONS: This heterocyclic compound serves as a valuable building block in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors where the methyl 7-chloroimidazo[1,5-a]pyridine-5-carboxylate scaffold facilitates ATP-competitive binding (European Journal of Medicinal Chemistry). In agrochemical research, derivatives of this compound have shown potential as herbicidal agents due to their ability to disrupt plant growth regulation pathways (Pest Management Science). Furthermore, its photostable characteristics make it suitable for incorporation into UV-absorbing formulations used in protective coatings and polymers (Journal of Applied Polymer Science).