1-methyl-2-(methylsulfonyl)-5-nitro-1H-imidazole
$300.00
CAS No.: 1615-53-8
Catalog No.: LT0237
Purity: 95%
MF: C5H7N3O4S
MW: 205.195
Storage: 2-8 degree Celsius
SMILES: CN1C(=NC=C1[N+](=O)[O-])S(=O)(=O)C
Catalog No.: LT0237
Purity: 95%
MF: C5H7N3O4S
MW: 205.195
Storage: 2-8 degree Celsius
SMILES: CN1C(=NC=C1[N+](=O)[O-])S(=O)(=O)C
CAS NO.: 1615-53-8;1-methyl-2-(methylsulfonyl)-5-nitro-1H-imidazole. PROPERTIES: This methylsulfonyl nitro imidazole presents as a white crystalline solid with a molecular weight of approximately 193.2 g/mol. The 1-methyl-2-(methylsulfonyl)-5-nitro-1H-imidazole combines methyl, methylsulfonyl, and nitro substituents on an imidazole ring. It exhibits limited aqueous solubility but good dissolution in polar aprotic solvents like DMSO and DMF. Stability characterization reveals sensitivity to reducing agents and light exposure, necessitating storage at 2-8 degree Celsius in amber glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 1-methyl-2-(methylsulfonyl)-5-nitro-1H-imidazole serves as a key intermediate in the synthesis of various pharmaceuticals. Its nitroimidazole framework provides opportunities for constructing antiparasitic agents and antibacterial drugs. Research teams utilize this compound as a starting material for creating nitroimidazole-based antibiotics and antiparasitic agents. The methylsulfonyl group enhances metabolic resistance in resulting drug candidates. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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