(2-butyl-4-chloro-1H-imidazol-5-yl)methanol
$200.00
CAS No.: 79047-41-9
Catalog No.: LT0254
Purity: 95%
MF: C8H13ClN2O
MW: 188.658
Storage: 2-8 degree Celsius
SMILES: C(CCC)C=1NC(=C(N1)Cl)CO
Catalog No.: LT0254
Purity: 95%
MF: C8H13ClN2O
MW: 188.658
Storage: 2-8 degree Celsius
SMILES: C(CCC)C=1NC(=C(N1)Cl)CO
CAS NO.: 79047-41-9;(2-butyl-4-chloro-1H-imidazol-5-yl)methanol. PROPERTIES: This chlorinated imidazole alcohol presents as a colorless liquid with a molecular weight of approximately 194.7 g/mol. The (2-butyl-4-chloro-1H-imidazol-5-yl)methanol combines a butylimidazole framework with a chloro substituent and a primary alcohol. It exhibits limited aqueous solubility but good dissolution in polar aprotic solvents like DMSO and DMF. Stability characterization reveals sensitivity to acid-catalyzed alcohol dehydration and base-promoted deprotonation of the imidazole ring, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause localized edema requiring corticosteroid application. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires chelation inhibitors and ophthalmology evaluation. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The (2-butyl-4-chloro-1H-imidazol-5-yl)methanol serves as a key intermediate in the synthesis of various pharmaceuticals. Its butylimidazole framework provides opportunities for constructing antifungal agents and H+/K+ ATPase inhibitors. Research teams utilize this compound as a starting material for creating proton pump inhibitors and antifungal drugs. The primary alcohol group undergoes oxidation to ketones or esterification for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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