1-methyl-2-(methylthio)-1H-imidazole
$320.00
CAS No.: 14486-52-3
Catalog No.: LT0236
Purity: 95%
MF: C5H8N2S
MW: 128.2
Storage: 2-8 degree Celsius
SMILES: CN1C(=NC=C1)SC
Catalog No.: LT0236
Purity: 95%
MF: C5H8N2S
MW: 128.2
Storage: 2-8 degree Celsius
SMILES: CN1C(=NC=C1)SC
CAS NO.: 14486-52-3;1-methyl-2-(methylthio)-1H-imidazole. PROPERTIES: This methylthio imidazole presents as a colorless liquid with a molecular weight of approximately 127.2 g/mol. The 1-methyl-2-(methylthio)-1H-imidazole combines methyl and methylthio substituents on an imidazole ring. It exhibits limited aqueous solubility but good dissolution in organic solvents like ethyl acetate and methanol. Stability characterization reveals sensitivity to oxidation and light exposure, necessitating storage at 2-8 degree Celsius in amber glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 1-methyl-2-(methylthio)-1H-imidazole serves as a key intermediate in the synthesis of various pharmaceuticals. Its imidazole framework provides opportunities for constructing antifungal agents and H+/K+ ATPase inhibitors. Research teams utilize this compound as a starting material for creating proton pump inhibitors and antifungal drugs. The methylthio group undergoes oxidation to sulfoxides or sulfones for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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