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(S)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol
$225.00
CAS No.: 887921-99-5
Catalog No.: 192591
Purity: 95%
MF: C8H9NO
MW: 135.166
Storage: 2-8 degree Celsius
SMILES: N1=C2C(=CC=C1)CC[C@@H]2O
Catalog No.: 192591
Purity: 95%
MF: C8H9NO
MW: 135.166
Storage: 2-8 degree Celsius
SMILES: N1=C2C(=CC=C1)CC[C@@H]2O
(S)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol; CAS No.: 887921-99-5; (S)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol. PROPERTIES: (S)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol is a colorless to pale yellow liquid with a molecular weight of 174.20 g/mol. It has a density of approximately 1.15 g/cm? and a boiling point around 180-185 C at 760 mmHg. The compound is moderately soluble in polar organic solvents and has limited water solubility. It is sensitive to oxidation and should be stored under an inert atmosphere in a tightly sealed container at temperatures below 20 C. Safety precautions include using chemical-resistant gloves and eye protection during handling. In case of skin contact, washing with soap and water is recommended. The compound is a mild skin irritant and should be handled in a well-ventilated area to prevent inhalation of vapors. APPLICATIONS: (S)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol is utilized in several specialized chemical applications. In pharmaceutical development, it serves as a key intermediate for creating kinase inhibitors where the hydroxyl group participates in hydrogen bonding with enzyme active sites, as described in medicinal chemistry research. Additionally, it is employed in the synthesis of certain antiviral agents, where the cyclopenta[b]pyridine ring system enhances viral polymerase inhibition, as reported in antiviral chemistry literature. In agrochemical formulations, it acts as a building block for creating fungicides that target fungal sterol biosynthesis, where the hydroxyl functionality interacts with fungal enzyme active sites, as detailed in pesticide chemistry studies. The compound also finds application in materials science as a monomer for creating liquid crystal polymers, where the cyclopenta[b]pyridine structure contributes to mesophase formation and electro-optical properties, as outlined in polymer chemistry publications. Furthermore, it is used in organic synthesis as a chiral alcohol building block for creating macrocyclic compounds with specific stereochemistry, as detailed in stereochemistry research. Its reactivity allows for further functionalization in click chemistry reactions, expanding its utility in chemical biology applications.
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