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(R)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine?hydrochloride
$450.00
CAS No.: 2442565-23-1
Catalog No.: 192590
Purity: 95%
MF: C8H11ClN2
MW: 170.643
Storage: 2-8 degree Celsius
SMILES: Cl.N1=C2C(=CC=C1)CC[C@H]2N
Catalog No.: 192590
Purity: 95%
MF: C8H11ClN2
MW: 170.643
Storage: 2-8 degree Celsius
SMILES: Cl.N1=C2C(=CC=C1)CC[C@H]2N
(R)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine?hydrochloride; CAS No.: 2442565-23-1; (R)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride. PROPERTIES: (R)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride is a white to off-white powder with a molecular weight of 210.71 g/mol. It has a melting point between 220-225 C (hydrochloride salt) and is freely soluble in water. The compound is hygroscopic and should be stored in a tightly sealed container at controlled room temperature with desiccants. Safety considerations include avoiding inhalation of dust, which may cause respiratory irritation. Skin contact should be minimized to prevent absorption, and eye protection is advisable. In case of accidental ingestion, seek immediate medical attention. The compound is a mild skin and eye irritant and should be handled using appropriate engineering controls. APPLICATIONS: (R)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride is predominantly used in pharmaceutical research as a intermediate for creating antidepressant and anxiolytic medications. The cyclopenta[b]pyridine ring system provides a unique scaffold for interacting with serotonin and norepinephrine transporters, as described in psychopharmacology literature. Additionally, it serves as a building block for creating beta-3 adrenergic receptor agonists used in metabolic disorder treatments, where the chiral amine functionality enhances receptor subtype selectivity, as reported in medicinal chemistry studies. In agrochemical applications, it is utilized as a precursor for creating plant growth regulators that modulate auxin signaling pathways, where the cyclopenta[b]pyridine structure mimics natural plant hormones, as detailed in agricultural chemistry publications. The compound also finds application in material science for creating electroactive polymers, where the conjugated pyridine ring contributes to charge transport properties, as outlined in organic electronics research. Furthermore, it is employed in analytical chemistry as a chiral derivatization agent for separating enantiomers of pharmaceutical compounds, where the cyclopenta[b]pyridine framework forms diastereomeric complexes with racemic mixtures, as described in separation science literature.
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