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6-chloro-1H-benzo[d]imidazole-4-carboxylicacid
$250.00
CAS No.: 180569-27-1
Catalog No.: 192603
Purity: 95%
MF: C8H5ClN2O2
MW: 196.593
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C2=C(NC=N2)C1)C(=O)O
Catalog No.: 192603
Purity: 95%
MF: C8H5ClN2O2
MW: 196.593
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C2=C(NC=N2)C1)C(=O)O
6-chloro-1H-benzo[d]imidazole-4-carboxylicacid; CAS No.: 180569-27-1; 6-chloro-1H-benzo[d]imidazole-4-carboxylicacid. PROPERTIES: 6-chloro-1H-benzo[d]imidazole-4-carboxylicacid is a white to off-white crystalline powder with a molecular weight of 198.60 g/mol. It has a melting point between 220-225 C and is moderately soluble in polar solvents like methanol and water. The compound is hygroscopic and should be stored in a tightly sealed container with desiccants at controlled room temperature. Safety precautions include avoiding skin contact and eye exposure, as it may cause irritation. In case of accidental ingestion, seek immediate medical attention. The compound is a mild skin irritant and should be handled in a well-ventilated area to prevent inhalation of dust. APPLICATIONS: 6-chloro-1H-benzo[d]imidazole-4-carboxylicacid is predominantly used in pharmaceutical synthesis as a intermediate for creating antiviral medications. The carboxylic acid group provides a handle for creating prodrugs that enhance oral bioavailability, as described in antiviral chemistry literature. Additionally, it serves as a building block for creating certain antiparasitic agents where the benzimidazole ring system interacts with parasite tubulin, as reported in parasitology research. In agrochemical applications, it is utilized as a precursor for creating herbicides that inhibit plant cell division, where the benzimidazole carboxylic acid disrupts microtubule formation, as detailed in agricultural chemistry publications. The compound also finds application in materials science as a monomer for creating electroactive polymers, where the benzimidazole structure contributes to charge transport properties, as outlined in organic electronics research. Furthermore, it is employed in analytical chemistry as a fluorescent probe for detecting certain metal ions, where the benzimidazole structure undergoes fluorescence changes upon metal binding, as described in analytical chemistry literature. Its structure makes it suitable for creating novel heterocycles through palladium-catalyzed cross-coupling reactions in chemical biology applications, as detailed in heterocyclic chemistry research.
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