3-(4-(trifluoromethoxy)phenoxy)azetidine
$1,200.00
CAS No.: 1346017-70-6
Catalog No.: 195277
Purity: 95%
MF: C10H10F3NO2
MW: 233.189
Storage: 2-8 degree Celsius
SMILES: FC(OC1=CC=C(OC2CNC2)C=C1)(F)F
Catalog No.: 195277
Purity: 95%
MF: C10H10F3NO2
MW: 233.189
Storage: 2-8 degree Celsius
SMILES: FC(OC1=CC=C(OC2CNC2)C=C1)(F)F
3-(4-(trifluoromethoxy)phenoxy)azetidine; CAS No.: 1346017-70-6; 3-(4-(trifluoromethoxy)phenoxy)azetidine. PROPERTIES: 3-(4-(trifluoromethoxy)phenoxy)azetidine appears as a colorless to pale yellow liquid with a slight amine odor. Its molecular formula is C10H11F3NO2, corresponding to a molecular weight of approximately 242.2 g/mol. The compound exhibits a boiling point around 140-145 C at 760 mmHg and a density of about 1.25 g/cm? at 25 C. It demonstrates moderate solubility in common organic solvents such as methanol, acetone, and diethyl ether but is sparingly soluble in water. The substance is sensitive to oxidation and may form explosive peroxides upon prolonged storage. Proper storage requires keeping it in a tightly sealed, amber glass container with a suitable stabilizer, in a cool, dry location away from direct sunlight and heat sources. The temperature should be maintained below 10 C if possible. Safety precautions include using chemical-resistant gloves, safety goggles, and lab coats to prevent skin absorption and inhalation of vapors. The compound may cause skin and eye irritation, and accidental ingestion may be harmful. In case of exposure, immediate rinsing with water and medical consultation is recommended. APPLICATIONS: 3-(4-(trifluoromethoxy)phenoxy)azetidine functions as a valuable intermediate in the synthesis of pharmaceuticals. Its azetidine and trifluoromethoxy groups provide structural features important for forming stable conjugates with biological targets. In biochemical research, it serves as a building block for creating enzyme inhibitors and prodrugs. Additionally, it finds application in the development of fluorescent probes for bioimaging, where its phenoxy and trifluoromethoxy groups allow for selective labeling of biological targets. The compound is also employed in the synthesis of agrochemicals, though specific applications in this area are limited to non-agricultural research settings.
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