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Fmoc-5-Ava-OH; 5-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanoic acid; CAS No.: 123622-48-0; Fmoc-5-Ava-OH. PROPERTIES: Fmoc-5-Ava-OH is a protected amino acid derivative used in peptide synthesis. This compound has a molecular weight of 324.38 g/mol and appears as a white to slightly yellowish solid. It is sparingly soluble in water but dissolves in organic solvents like DMF and dichloromethane. Fmoc-5-Ava-OH should be stored at room temperature in a dry environment. It is sensitive to moisture and light. Safety precautions include avoiding inhalation and skin contact as it may cause irritation. APPLICATIONS: Fmoc-5-Ava-OH serves as a monomer in the synthesis of peptides containing 5-aminovaleric acid residues. In medicinal chemistry, it facilitates the creation of peptidomimetics with extended linker regions between functional groups. In research applications, Fmoc-5-Ava-OH is used to prepare peptides for studying conformational flexibility and distance constraints in biomolecular interactions. These applications are referenced in peptide chemistry literature and synthetic organic chemistry publications.