2,2-dimethylsuccinic 1-methyl ester
$250.00
CAS No.: 32980-26-0
Catalog No.: 196728
Purity: 95%
MF: C7H12O4
MW: 160.169
Storage: 2-8 degree Celsius
SMILES: COC(C(CC(=O)O)(C)C)=O
Catalog No.: 196728
Purity: 95%
MF: C7H12O4
MW: 160.169
Storage: 2-8 degree Celsius
SMILES: COC(C(CC(=O)O)(C)C)=O
2,2-dimethylsuccinic 1-methyl ester; CAS No.: 32980-26-0; 2,2-dimethylsuccinic 1-methyl ester. PROPERTIES: This dimethyl-substituted succinic ester features molecular formula C?H??O? with molecular weight 160.18 g/mol. It generally appears as a colorless liquid. Soluble in polar aprotic solvents like ethyl acetate and dichloromethane. Boiling point approximately 140-145 C. Exhibits IR absorption for ester (~1750 cm??) and C-H stretches. Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, 2,2-dimethylsuccinic 1-methyl ester should be stored at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a dimethyl-substituted succinic ester, 2,2-dimethylsuccinic 1-methyl ester is predominantly utilized in the synthesis of pharmaceutical intermediates. It serves as a key building block for constructing statin drugs, where the ester groups undergo hydrolysis and further functionalization to form the characteristic lactone ring (Journal of Medicinal Chemistry). Additionally, the compound participates in the synthesis of fluorescent probes for bioimaging applications, where its ester functionality enables conjugation to biomolecules via enzymatic hydrolysis (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the dimethyl groups contribute to improved flame retardancy and mechanical properties (Polymer International). Furthermore, the compound serves as a starting material in the development of succinic ester-based plasticizers for polymer applications requiring specific flexibility and thermal properties (Polymer Chemistry).
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