3-tert-butylcyclobutanone
$350.00
CAS No.: 20614-90-8
Catalog No.: 195560
Purity: 95%
MF: C8H14O
MW: 126.199
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)C1CC(C1)=O
Catalog No.: 195560
Purity: 95%
MF: C8H14O
MW: 126.199
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)C1CC(C1)=O
3-tert-butylcyclobutanone; CAS No.: 20614-90-8; 3-tert-butylcyclobutanone. PROPERTIES: 3-tert-butylcyclobutanone is a colorless liquid with molecular formula C9H16O. It exhibits a boiling point around 105-110 C at 760 mmHg and good thermal stability. The compound shows good solubility in ketones like acetone and moderate solubility in aliphatic hydrocarbons. Recommended storage conditions include maintaining temperatures below 30 C in sealed containers. Safety considerations involve using explosion-proof equipment when handling due to its flammability and employing proper engineering controls to minimize vapor release. APPLICATIONS: This tert-butyl-substituted cyclobutanone serves as a key intermediate in the synthesis of vitamin D analogs, where the 3-tert-butylcyclobutanone group provides steric protection to the sensitive steroid core (Journal of Steroid Biochemistry and Molecular Biology). In organic synthesis, the compound is used as a building block for constructing medium-sized carbocycles through ring-expansion reactions (Synthesis). Furthermore, its ketone functionality enables oximation reactions for the development of bioactive hydroxylamine derivatives used in anti-tuberculosis research (Antimicrobial Agents and Chemotherapy).
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