(1S,2S)-2-aminocyclobutan-1-ol hydrochloride
$500.00
CAS No.: 1820572-14-2
Catalog No.: 195561
Purity: 95%
MF: C4H10ClNO
MW: 123.583
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@@H]1[C@H](CC1)O
Catalog No.: 195561
Purity: 95%
MF: C4H10ClNO
MW: 123.583
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@@H]1[C@H](CC1)O
(1S,2S)-2-aminocyclobutan-1-ol hydrochloride; CAS No.: 1820572-14-2; (1S,2S)-2-aminocyclobutan-1-ol hydrochloride. PROPERTIES: (1S,2S)-2-aminocyclobutan-1-ol hydrochloride appears as white crystals with molecular formula C4H10ClNO. It exhibits a melting point around 185-188 C and moderate thermal stability. The compound shows good solubility in water and moderate solubility in methanol. Recommended storage requires keeping it in tightly sealed containers at room temperature. Safety precautions involve avoiding skin contact with the hydrochloride salt due to potential irritation and using appropriate eye protection. APPLICATIONS: This chiral amino alcohol serves as a valuable intermediate in the synthesis of ACE inhibitors for hypertension treatment, where the (1S,2S)-2-aminocyclobutan-1-ol hydrochloride group contributes to angiotensin-converting enzyme binding (Journal of Medicinal Chemistry). In asymmetric catalysis, the compound is used as a chiral ligand for transition metal-catalyzed asymmetric hydrogenation reactions, achieving high enantioselectivities in various substrates (Catalysis Science & Technology). Furthermore, its amino alcohol functionality enables reductive amination reactions for the preparation of diverse secondary amines used in medicinal chemistry library development (ACS Combinatorial Science).
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