3-(methoxymethyl)cyclobutan-1-amine
$320.00
CAS No.: 1209654-41-0
Catalog No.: 195555
Purity: 95%
MF: C6H13NO
MW: 115.176
Storage: 2-8 degree Celsius
SMILES: COCC1CC(C1)N
Catalog No.: 195555
Purity: 95%
MF: C6H13NO
MW: 115.176
Storage: 2-8 degree Celsius
SMILES: COCC1CC(C1)N
3-(methoxymethyl)cyclobutan-1-amine; CAS No.: 1209654-41-0; 3-(methoxymethyl)cyclobutan-1-amine. PROPERTIES: 3-(methoxymethyl)cyclobutan-1-amine is a colorless oil with molecular formula C6H13NO. It demonstrates a boiling point around 90-95 C at 10 mmHg and moderate thermal stability. The compound exhibits good solubility in polar aprotic solvents like DMSO and moderate solubility in methanol. Recommended storage requires keeping it in tightly sealed containers at 2-8 C under nitrogen atmosphere to prevent oxidation. Safety precautions involve avoiding prolonged skin contact and using chemical splash goggles to prevent eye injury from splashing liquids. APPLICATIONS: This methoxymethyl-protected cyclobutane amine serves as a valuable intermediate in the synthesis of beta-lactamase inhibitors, where the 3-(methoxymethyl)cyclobutan-1-amine group provides steric protection to the beta-lactam core (Journal of Medicinal Chemistry). In asymmetric catalysis, the compound is used as a chiral amine catalyst for asymmetric amination reactions, achieving high enantioselectivities in various substrates (Catalysis Science & Technology). Furthermore, its amine functionality enables reductive amination reactions for the preparation of diverse secondary amines used in medicinal chemistry library development (ACS Combinatorial Science).
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