Azido-PEG4-NHS ester
$250.00
CAS No.: 944251-24-5
Catalog No.: 198520
Purity: 95%
MF: C15H24N4O8
MW: 388.377
Storage: 2-8 degree Celsius
SMILES: N(=[N+]=[N-])CCOCCOCCOCCOCCC(=O)ON1C(CCC1=O)=O
Catalog No.: 198520
Purity: 95%
MF: C15H24N4O8
MW: 388.377
Storage: 2-8 degree Celsius
SMILES: N(=[N+]=[N-])CCOCCOCCOCCOCCC(=O)ON1C(CCC1=O)=O
CAS No.: 944251-24-5; Azido-PEG4-NHS ester. PROPERTIES: Generally a colorless to pale yellow viscous liquid. Molecular weight around 580 g/mol. Soluble in DMF and DMSO, sparingly soluble in water. Requires storage at -20 C protected from moisture. Safety measures include using acid-resistant gloves and avoiding skin contact. May cause severe skin burns and eye damage. APPLICATIONS: Functions as a PEGylation reagent with azide functionality. The Azido-PEG4-NHS ester enables modification of primary amines on proteins and nanoparticles via NHS ester chemistry followed by click reactions as detailed in bioconjugation protocols. In immunoassay development, it is used to create PEGylated detection antibodies with reduced non-specific binding according to analytical chemistry research. Furthermore, this compound is valuable in developing site-specific antibody-drug conjugates using bioorthogonal ligation strategies as reported in medicinal chemistry literature.
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