Allisartan isoproxil
$300.00
CAS No.: 947331-05-7
Catalog No.: LT0138
Purity: 95%
MF: C27H29ClN6O5
MW: 553.019
Storage: 2-8 degree Celsius
SMILES: N=1NN=NC1C1=C(C=CC=C1)C1=CC=C(C=C1)CN1C(=NC(=C1C(=O)OCOC(=O)OC(C)C)Cl)CCCC
Catalog No.: LT0138
Purity: 95%
MF: C27H29ClN6O5
MW: 553.019
Storage: 2-8 degree Celsius
SMILES: N=1NN=NC1C1=C(C=CC=C1)C1=CC=C(C=C1)CN1C(=NC(=C1C(=O)OCOC(=O)OC(C)C)Cl)CCCC
CAS No.: 947331-05-7; Allisartan isoproxil. PROPERTIES: Allisartan isoproxil is an angiotensin II receptor antagonist with molecular formula C27H31N3O5. This white to pale yellow powder has a molecular weight of approximately 473.5 g/mol. It exhibits moderate solubility in water and common pharmaceutical solvents. The compound is sensitive to moisture and should be stored at room temperature in airtight containers. Safety precautions include wearing a dust mask and avoiding inhalation. Allisartan isoproxil is classified as a Category 4 drug hazard. APPLICATIONS: In cardiovascular research, Allisartan isoproxil serves as a tool compound for studying renin-angiotensin system modulation, as documented in Hypertension. Its application in developing therapies for resistant hypertension is reported in Journal of Human Hypertension. In pharmacogenomics, the reagent enables analysis of genetic polymorphisms affecting response to angiotensin receptor blockers, with findings published in Pharmacogenomics Journal. Additionally, it has applications in studying organ protection effects in diabetic nephropathy, as described in Kidney International.
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