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5-(trifluoromethyl)quinolin-6-amine; CAS No.: 155793-47-8; 5-(trifluoromethyl)quinolin-6-amine. PROPERTIES: 5-(trifluoromethyl)quinolin-6-amine is a crystalline powder with molecular formula C10H6F3N3. It has a melting point between 145-150 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored under nitrogen atmosphere at 5-15 C to prevent oxidative degradation. Safety considerations include avoiding contact with strong acids and using protective equipment as this compound may cause serious eye damage. APPLICATIONS: This trifluoromethyl-substituted quinoline amine is employed in the synthesis of kinase inhibitors. The amine group provides critical interactions with the enzyme's active site as described in cancer research literature. In materials science, 5-(trifluoromethyl)quinolin-6-amine derivatives have found application in creating electron-transport materials for organic photovoltaics. According to materials chemistry journals, the electron-withdrawing trifluoromethyl group improves charge transport properties while the quinoline scaffold provides structural rigidity.