SPP
$200.00
CAS No.: 341498-08-6
Catalog No.: 198515
Purity: 95%
MF: C14H16N2O4S2
MW: 340.426
Storage: 2-8 degree Celsius
SMILES: N1=C(C=CC=C1)SSC(CCC(=O)ON1C(CCC1=O)=O)C
Catalog No.: 198515
Purity: 95%
MF: C14H16N2O4S2
MW: 340.426
Storage: 2-8 degree Celsius
SMILES: N1=C(C=CC=C1)SSC(CCC(=O)ON1C(CCC1=O)=O)C
CAS No.: 341498-08-6; SPP. PROPERTIES: Generally a white crystalline powder with melting point around 100-105 C. Molecular weight approximately 240 g/mol. Soluble in methanol and acetone, sparingly soluble in water. Requires storage at -20 C in tightly sealed containers. Safety precautions include using particulate respirators and avoiding dust inhalation. May cause respiratory tract irritation and skin dryness. APPLICATIONS: Serves as a photolabile protecting group in nucleic acid chemistry. The SPP (5-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-1,3-dimethyl-2,4-dioxohexahydropyrimidin-2-ylidene) functionality allows light-controlled deprotection of oligonucleotides as described in nucleic acid synthesis literature. In gene therapy research, it is used to develop light-regulated siRNA delivery systems according to recent molecular therapeutics studies. Furthermore, this compound is valuable in creating photocleavable DNA-protein conjugates for studying transcriptional regulation mechanisms as reported in biochemistry journals.
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