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5-iodopyrimidin-4-amine; CAS No.: 91416-96-5; 5-iodopyrimidin-4-amine. PROPERTIES: 5-iodopyrimidin-4-amine has molecular formula C4H4IN3 with molecular weight approximately 233.0 g/mol. It typically forms white to off-white solids with a reported melting point of 192-195 C. The compound demonstrates limited solubility in water but dissolves in polar aprotic solvents like DMSO. Proper storage requires a tightly sealed container at room temperature away from light and moisture. Safety considerations involve using personal protective equipment during handling to prevent skin and eye contact, as it may cause mild irritation. The amine group may react with electrophilic substances, so compatibility should be verified. In case of accidental release, absorb with inert material and dispose of properly. APPLICATIONS: 5-iodopyrimidin-4-amine serves as a key intermediate in the synthesis of antiviral agents. Its iodine substituent provides valuable reactivity for further chemical modification. In pharmaceutical research, it has been employed in developing novel antiviral compounds targeting RNA viruses, as documented in virology-focused medicinal chemistry journals. The pyrimidin-4-amine structure enables hydrogen bonding interactions critical for biological activity. Additionally, this compound acts as a building block for specialty chemicals, with applications reported in fine chemical literature focusing on heterocyclic compounds for material science.