5-bromo-4,6-dimethylpyrimidin-2-amine
$300.00
CAS No.: 4214-57-7
Catalog No.: 196437
Purity: 95%
MF: C6H8BrN3
MW: 202.055
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC(=NC1C)N)C
Catalog No.: 196437
Purity: 95%
MF: C6H8BrN3
MW: 202.055
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC(=NC1C)N)C
5-bromo-4,6-dimethylpyrimidin-2-amine; CAS No.: 4214-57-7; 5-bromo-4,6-dimethylpyrimidin-2-amine. PROPERTIES: 5-bromo-4,6-dimethylpyrimidin-2-amine possesses molecular formula C6H7BrN3 with a molecular weight of approximately 215.04 g/mol. It generally appears as colorless crystals with a reported melting point of 102-105 C. The compound exhibits good solubility in common organic solvents like acetone and ethyl acetate but poor water solubility. Proper storage involves keeping in a tightly sealed container at room temperature, protected from light and moisture. Safety precautions include avoiding release to the environment and using personal protective equipment during handling. The amine group may react with electrophiles, so compatibility with acidic conditions should be verified. In case of skin contact, thorough washing with soap and water is recommended. APPLICATIONS: 5-bromo-4,6-dimethylpyrimidin-2-amine acts as a key intermediate in the synthesis of agricultural chemicals (though non-agricultural applications are emphasized here) and pharmaceuticals. Its bromine substituent enables participation in Suzuki-Miyaura coupling reactions. In medicinal chemistry, it has been used to develop novel kinase inhibitors, as reported in oncology-focused pharmaceutical research journals. The dimethyl substituents improve membrane permeability in bioactive molecules. Additionally, this compound serves as a precursor for veterinary pharmaceuticals, with applications described in veterinary medicinal chemistry literature focusing on antiparasitic agents.
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