5-bromo-6-chloropyrimidin-4(3H)-one
$300.00
CAS No.: 89089-19-0
Catalog No.: 196439
Purity: 95%
MF: C4H2BrClN2O
MW: 209.43
Storage: 2-8 degree Celsius
SMILES: BrC=1C(NC=NC1Cl)=O
Catalog No.: 196439
Purity: 95%
MF: C4H2BrClN2O
MW: 209.43
Storage: 2-8 degree Celsius
SMILES: BrC=1C(NC=NC1Cl)=O
5-bromo-6-chloropyrimidin-4(3H)-one; CAS No.: 89089-19-0; 5-bromo-6-chloropyrimidin-4(3H)-one. PROPERTIES: 5-bromo-6-chloropyrimidin-4(3H)-one has molecular formula C4H2BrClN3O with molecular weight approximately 236.44 g/mol. It typically forms white crystalline solids with a melting point ranging from 185-188 C. The compound shows limited solubility in water but dissolves in polar aprotic solvents like DMSO and DMF. Recommended storage conditions include maintaining in a tightly sealed container at 2-8 C to preserve stability. Safety considerations involve using respiratory protection when handling powder forms to prevent inhalation, which may cause respiratory tract irritation. The compound's reactivity profile requires caution when combining with reducing agents. In case of eye contact, immediate flushing with water for at least 15 minutes is advised. APPLICATIONS: 5-bromo-6-chloropyrimidin-4(3H)-one functions as a valuable intermediate in the development of antimicrobial agents. Its halogen substituents provide versatile reaction sites for further functionalization. In pharmaceutical research, it has been utilized to create novel antibacterial compounds targeting Gram-negative pathogens, as documented in medicinal chemistry journals specializing in infectious disease treatments. The pyrimidinone structure enables hydrogen bonding interactions critical for biological activity. Additionally, this compound serves as a building block for fluorescent dyes, with applications reported in chemical literature focusing on heterocyclic fluorescent markers for bioimaging.
Reviews
Write Your Own Review