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4-hydroxy-2-nitrobenzoic acid; CAS No.: 74230-08-3; 4-hydroxy-2-nitrobenzoic acid. PROPERTIES: 4-hydroxy-2-nitrobenzoic acid is a yellow crystalline solid with a molecular formula of C7H5NO4. It has a molecular weight of 171.12 g/mol and a melting point of approximately 225-228 C. The compound exhibits moderate solubility in water and is more soluble in polar organic solvents like methanol and ethanol. It is sensitive to reducing conditions and should be stored below 25 C in a tightly sealed container, protected from light and moisture. Safety precautions include using gloves and eye protection. It is classified as an oxidizing agent (Oxidation category 2) and a category 2 eye irritant. APPLICATIONS: 4-hydroxy-2-nitrobenzoic acid serves as a key intermediate in the synthesis of various antimicrobial agents used in pharmaceutical applications. Its nitro group provides essential electron-withdrawing effects for antimicrobial activity. In the field of materials science, this compound is used in the preparation of polymeric materials with enhanced UV-absorbing properties, as documented in Polymer Chemistry. It also functions as a building block for the synthesis of fluorescent probes for detecting biological thiols, where its carboxylic acid group facilitates conjugation to biomolecules. Additionally, the compound is employed in the development of novel electrochemical sensors for environmental monitoring applications, where its redox-active nitro group participates in electron transfer processes. Its unique electronic properties make it valuable in the synthesis of metal-organic frameworks (MOFs) for gas storage applications, as reported in the journal Chemical Materials, where its carboxylic acid group coordinates with metal centers to form porous structures.