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3-chloro-2-nitrobenzaldehyde; CAS No.: 22233-52-9 3-chloro-2-nitrobenzaldehyde. PROPERTIES: 3-chloro-2-nitrobenzaldehyde is a crystalline solid with a molecular weight of 183.6 g/mol. It has a melting point in the range of 55-60 C and exhibits low water solubility. The compound is moderately soluble in organic solvents such as methylene chloride and acetone. When handling 3-chloro-2-nitrobenzaldehyde, extreme caution is required due to its potential toxicity and reactivity. Protective equipment including gloves, eye protection, and a lab coat should be worn. The compound should be stored in a tightly sealed container at temperatures below 10 C in a cool, dark place. It is sensitive to heat and may decompose upon exposure to high temperatures, releasing toxic fumes. APPLICATIONS: 3-chloro-2-nitrobenzaldehyde is widely used as a synthetic intermediate in the production of pharmaceuticals and dyes. Its nitro and chloro groups provide multiple sites for chemical modification, enabling diverse reaction pathways. Derivatives of this compound have been explored in the development of antimicrobial agents, as reported in the Journal of Antimicrobial Chemotherapy. The aldehyde functionality allows for condensation reactions to form Schiff bases, which have been investigated for their potential in metal ion chelation and sensor development, as highlighted in Inorganic Chemistry. Additionally, the compound serves as a building block for the synthesis of heterocyclic compounds used in organic electronics, as described in Advanced Materials.