3-(2,4-dimethoxyphenyl)propanoic acid; CAS No.: 22174-29-4 3-(2,4-dimethoxyphenyl)propanoic acid. PROPERTIES: 3-(2,4-dimethoxyphenyl)propanoic acid is a crystalline solid with a molecular weight of 212.2 g/mol. It has a melting point between 125-130 C and exhibits moderate water solubility. The compound is more soluble in polar organic solvents like methanol and ethyl acetate. When handling 3-(2,4-dimethoxyphenyl)propanoic acid, it is advisable to work in a well-ventilated area with standard laboratory protective equipment. The compound should be stored in a tightly sealed container at room temperature, preferably below 30 C. It is sensitive to acidic conditions, which may cause hydrolysis of the ester groups. APPLICATIONS: 3-(2,4-dimethoxyphenyl)propanoic acid serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals, though applications focus on non-agricultural uses. Its methoxy-substituted phenyl group provides electron-donating characteristics that enhance binding to biological targets. Derivatives of this compound have been explored in the development of anti-inflammatory agents, as documented in the Journal of Medicinal Chemistry. The carboxylic acid functionality allows for formation of amide and ester bonds, making it useful in peptide synthesis and the preparation of prodrugs, as reported in Bioorganic & Medicinal Chemistry. Additionally, the compound can be utilized in the synthesis of liquid crystalline materials for display technologies, as highlighted in Liquid Crystals.