3-bromo-7-methoxyquinoline
$300.00
CAS No.: 959121-99-4
Catalog No.: 191985
Purity: 95%
MF: C10H8BrNO
MW: 238.084
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC2=CC(=CC=C2C1)OC
Catalog No.: 191985
Purity: 95%
MF: C10H8BrNO
MW: 238.084
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC2=CC(=CC=C2C1)OC
3-bromo-7-methoxyquinoline; CAS No.: 959121-99-4;3-bromo-7-methoxyquinoline. PROPERTIES: 3-bromo-7-methoxyquinoline is a halogenated quinoline ether with molecular formula C10H7BrNO. This crystalline material typically appears as pale yellow powder and has a melting point between 85-90 C. The molecule contains a quinoline core with a bromine atom at position 3 and a methoxy group at position 7. The 3-bromo-7-methoxyquinoline exhibits moderate basic character due to the quinoline nitrogen, with a pKa value around 4.0 for the conjugate acid. It demonstrates good solubility in common organic solvents like ethyl acetate and limited solubility in water. Proper storage requires keeping in a tightly sealed container with inert atmosphere, stored below 15 C to prevent oxidative degradation. Safety precautions include using N95 respiratory protection and chemical-resistant gloves, as the compound may cause respiratory irritation and skin burns. According to EU safety regulations, it carries H314 and H335 hazard statements for causing severe skin burns and respiratory tract irritation. APPLICATIONS: The 3-bromo-7-methoxyquinoline molecule serves as a valuable intermediate in the synthesis of quinoline-based kinase inhibitors, as reported in medicinal chemistry research focusing on oncology drug development. The bromo substituent provides a site for further functionalization via cross-coupling reactions. Additionally, 3-bromo-7-methoxyquinoline derivatives have been investigated for their potential as fluorescent probes for bioimaging applications, as described in analytical chemistry publications. The compound's ability to form coordination complexes with metal ions has also made it useful in developing chemical sensors for metal detection, as documented in materials science studies emphasizing selective ion recognition.
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