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methyl 6-aminoquinoline-3-carboxylate; CAS No.: 1170979-26-6; methyl 6-aminoquinoline-3-carboxylate. PROPERTIES: Methyl 6-aminoquinoline-3-carboxylate is a yellow crystalline solid with a molecular weight of 216.23 g/mol. It is soluble in chloroform and acetone but poorly soluble in water. The amino and ester groups confer sensitivity to oxidation and hydrolysis, requiring storage under nitrogen at ?20 C. Prolonged exposure to air may lead to discoloration and reduced purity. Safety protocols mandate using chemical-resistant gloves and avoiding inhalation during weighing. APPLICATIONS: This compound is critical in synthesizing antimalarial and antitumor agents, leveraging its quinoline core for DNA intercalation, as described in Novartis research. Its amino group facilitates conjugation with fluorescent tags, enabling use in bioimaging probes, as noted in Chemical Communications.