3-bromo-4,5-difluorobenzonitrile
$350.00
CAS No.: 1349715-72-5
Catalog No.: 193980
Purity: 95%
MF: C7H2BrF2N
MW: 218
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C#N)C=C(C1F)F
Catalog No.: 193980
Purity: 95%
MF: C7H2BrF2N
MW: 218
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C#N)C=C(C1F)F
3-bromo-4,5-difluorobenzonitrile; CAS No.: 1349715-72-5;3-bromo-4,5-difluorobenzonitrile. PROPERTIES: 3-bromo-4,5-difluorobenzonitrile is a brominated and fluorinated aromatic nitrile with molecular formula C7H3BrF2NO. It typically exists as a colorless liquid with a boiling point around 140-145 C. The compound has limited water solubility but dissolves well in organic solvents like dichloromethane or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic bromine and fluorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 20 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic systems. The bromo and difluoro substituents provide multiple sites for cross-coupling and nucleophilic substitution reactions, while the nitrile group offers additional functionality for further elaboration (The Journal of Organic Chemistry). In pharmaceutical development, 3-bromo-4,5-difluorobenzonitrile contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).
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