2-hydroxy-3-(trifluoromethoxy)benzaldehyde
$200.00
CAS No.: 497959-31-6
Catalog No.: 193934
Purity: 95%
MF: C8H5F3O3
MW: 206.119
Storage: 2-8 degree Celsius
SMILES: OC1=C(C=O)C=CC=C1OC(F)(F)F
Catalog No.: 193934
Purity: 95%
MF: C8H5F3O3
MW: 206.119
Storage: 2-8 degree Celsius
SMILES: OC1=C(C=O)C=CC=C1OC(F)(F)F
2-hydroxy-3-(trifluoromethoxy)benzaldehyde; CAS No.: 497959-31-6;2-hydroxy-3-(trifluoromethoxy)benzaldehyde. PROPERTIES: 2-hydroxy-3-(trifluoromethoxy)benzaldehyde is a hydroxylated and trifluoromethylated aromatic aldehyde with molecular formula C8H5F3O3. It typically exists as a white to off-white crystalline powder with a melting point of approximately 100-105 C. The compound has limited water solubility but dissolves in basic aqueous solutions. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic fluorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from moisture and heat. APPLICATIONS: In pharmaceutical research, this compound serves as a lead structure for developing antimicrobial and anticancer agents. The hydroxy and trifluoromethoxy substitution provides structural diversity that enhances binding to biological targets, while the aldehyde group forms the pharmacophore essential for activity (European Journal of Medicinal Chemistry). In materials science, 2-hydroxy-3-(trifluoromethoxy)benzaldehyde contributes to the creation of functional organic materials with tailored electronic properties. Its fluorinated aromatic core and aldehyde group influence the electronic characteristics of derived materials, useful in optoelectronic applications such as organic light-emitting diodes (Journal of Materials Chemistry C). The hydroxyl group enables further functionalization through esterification or etherification, expanding its utility in multistep syntheses (The Journal of Organic Chemistry).
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