2,3,6-trifluoroaniline
$250.00
CAS No.: 67815-56-9
Catalog No.: 193852
Purity: 95%
MF: C6H4F3N
MW: 147.099
Storage: 2-8 degree Celsius
SMILES: FC1=C(N)C(=CC=C1F)F
Catalog No.: 193852
Purity: 95%
MF: C6H4F3N
MW: 147.099
Storage: 2-8 degree Celsius
SMILES: FC1=C(N)C(=CC=C1F)F
2,3,6-trifluoroaniline; CAS No.: 67815-56-9;2,3,6-trifluoroaniline. PROPERTIES: 2,3,6-trifluoroaniline is a fluorinated aromatic amine with molecular formula C6H4F3N. It typically exists as a colorless liquid with a mild amine odor, having a boiling point around 100-105 C. The compound has limited water solubility but dissolves in organic solvents like dichloromethane or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong oxidizing agents, releasing toxic fluorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic molecules. The trifluoro substitution provides strong electron-withdrawing effects that influence reactivity and selectivity in coupling reactions, while the amine group offers sites for further functionalization (Tetrahedron Letters). In pharmaceutical development, 2,3,6-trifluoroaniline contributes to the synthesis of antimicrobial and anticancer agents where the halogenated aromatic scaffold enhances binding to biological targets (Journal of Medicinal Chemistry). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).
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