1-chloro-2-fluoro-4-nitrobenzene
$300.00
CAS No.: 350-31-2
Catalog No.: 196639
Purity: 95%
MF: C6H3ClFNO2
MW: 175.546
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C=C(C=C1)[N+](=O)[O-])F
Catalog No.: 196639
Purity: 95%
MF: C6H3ClFNO2
MW: 175.546
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C=C(C=C1)[N+](=O)[O-])F
1-chloro-2-fluoro-4-nitrobenzene; CAS No.: 350-31-2; 1-chloro-2-fluoro-4-nitrobenzene. PROPERTIES: This polyhalogenated nitroaromatic compound possesses molecular formula C6H3ClFNO2 with molecular weight 176.54 g/mol. It generally appears as colorless to pale yellow liquid, exhibiting characteristic nitro group reactivity. The compound demonstrates solubility in non-polar and slightly polar organic solvents like hexanes and dichloromethane, while being sparingly soluble in water. Its boiling point ranges between 140-145 C at 760 mmHg, and it exhibits IR absorption bands corresponding to the nitro group (~1520 and ~1350 cm??) and aromatic C-H stretches. Thermogravimetric analysis indicates decomposition onset above 150 C under nitrogen atmosphere. For optimal stability, 1-chloro-2-fluoro-4-nitrobenzene should be stored at 2-8 C in tightly sealed glass containers, protected from moisture and prolonged light exposure. As with nitro compounds, it may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: The nitro group of 1-chloro-2-fluoro-4-nitrobenzene makes it particularly effective as a building block in aromatic substitution reactions. It serves as key intermediate in the preparation of azo dyes, where the nitro group undergoes reduction to amine followed by diazotization and coupling reactions to form colorful azo derivatives as demonstrated in dye chemistry research (Dyes and Pigments). Additionally, the compound participates in the synthesis of pharmaceutical intermediates, where its chloro and fluoro substituents provide valuable directing effects for further functionalization (Journal of Fluorine Chemistry). In materials science, it functions as monomer for preparing polyaryl ethers with enhanced thermal stability, where the nitro group contributes to improved flame retardancy and mechanical properties (Polymer International). Furthermore, the compound serves as starting material in the development of nitroaromatic explosives with specialized applications in controlled detonation processes (Propellants, Explosives, Pyrotechnics).
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