1-(5-amino-2-hydroxyphenyl)ethanone
$300.00
CAS No.: 50-80-6
Catalog No.: 194964
Purity: 95%
MF: C8H9NO2
MW: 151.165
Storage: 2-8 degree Celsius
SMILES: NC=1C=CC(=C(C1)C(C)=O)O
Catalog No.: 194964
Purity: 95%
MF: C8H9NO2
MW: 151.165
Storage: 2-8 degree Celsius
SMILES: NC=1C=CC(=C(C1)C(C)=O)O
1-(5-amino-2-hydroxyphenyl)ethanone; CAS No.: 50-80-6; 1-(5-amino-2-hydroxyphenyl)ethanone. PROPERTIES: 1-(5-amino-2-hydroxyphenyl)ethanone presents as fine needle-like crystals with molecular formula C8H9NO2. It has a melting point of approximately 210-212 C and demonstrates moderate solubility in polar organic solvents while being practically insoluble in non-polar media. The compound is hygroscopic and prone to oxidation upon exposure to air and light. Recommended storage involves vacuum-sealed ampules with desiccants maintained at -20 C. From a safety standpoint, this compound exhibits moderate skin and eye irritation potential. Inhalation of dust may cause respiratory tract discomfort. It is classified as harmful if swallowed (LD50 ~200 mg/kg). Precautions include using powder respirators, PVC gloves, and protective eyewear with side shields during handling. APPLICATIONS: In the field of organic synthesis, 1-(5-amino-2-hydroxyphenyl)ethanone serves as a versatile precursor for constructing flavonoid frameworks. The compound's amino and hydroxy functionalities enable condensation reactions to form C-glycosyl flavones with potential neuroprotective activities (Bioorganic & Medicinal Chemistry). Additionally, this ketone derivative finds application in the synthesis of certain semicarbazone complexes used as analytical reagents for metal ion detection. The formation of colored coordination complexes with transition metals allows for spectrophotometric determination with detection limits as low as 0.1 ppm (Analytical Chemistry). In cosmetic formulations, derivatives of this compound provide skin conditioning benefits through controlled release of salicylic acid moieties when appropriately esterified.
Reviews
Write Your Own Review