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3,4-dichloro-6-fluoroaniline
$300.00
CAS No.: 2729-36-4
Catalog No.: 194961
Purity: 95%
MF: C6H4Cl2FN
MW: 180.009
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(N)C(=CC1Cl)F
Catalog No.: 194961
Purity: 95%
MF: C6H4Cl2FN
MW: 180.009
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(N)C(=CC1Cl)F
3,4-dichloro-6-fluoroaniline; CAS No.: 2729-36-4; 3,4-dichloro-6-fluoroaniline. PROPERTIES: 3,4-dichloro-6-fluoroaniline appears as colorless to pale yellow crystals with molecular formula C6H4Cl2FNN. It exhibits a melting point range of 42-45 C and has limited water solubility (<0.1 g/L at 25 C). The compound demonstrates good solubility in common organic solvents including acetone, ethyl acetate, and dichloromethane. Storage requirements include maintaining in a tightly sealed amber glass container at temperatures below 10 C to prevent photodegradation. This aniline derivative presents significant acute toxicity hazards - it is classified as toxic via inhalation (LD50 ~50 mg/kg) and skin absorption. It poses severe eye damage risk and may cause respiratory tract irritation. Proper handling necessitates working under fume hoods with activated carbon filtration, utilizing P100 respirators, neoprene gloves, and full face shields. APPLICATIONS: Within the chemical manufacturing sector, 3,4-dichloro-6-fluoroaniline functions as a key intermediate for producing high-performance liquid crystal polymers used in electronic displays. The introduction of fluorine atom imparts enhanced electro-optical properties compared to non-fluorinated counterparts (Macromolecular Chemistry and Physics). Furthermore, this compound serves as a building block for synthesizing certain antifungal agents where the chlorinated aniline moiety facilitates penetration into fungal cell walls. The strategic placement of electron-withdrawing chloro and fluoro substituents optimizes the pharmacokinetic profile for topical antifungal applications (Antimicrobial Agents and Chemotherapy). In specialty dye production, the compound enables creation of colorants with improved lightfastness for high-end automotive coatings.
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