1,3-dimethyl-2-bromo-4-nitrobenzene
$250.00
CAS No.: 60956-25-4
Catalog No.: 193828
Purity: 95%
MF: C8H8BrNO2
MW: 230.061
Storage: 2-8 degree Celsius
SMILES: CC1=C(C(=C(C=C1)[N+](=O)[O-])C)Br
Catalog No.: 193828
Purity: 95%
MF: C8H8BrNO2
MW: 230.061
Storage: 2-8 degree Celsius
SMILES: CC1=C(C(=C(C=C1)[N+](=O)[O-])C)Br
1,3-dimethyl-2-bromo-4-nitrobenzene; CAS No.: 60956-25-4;1,3-dimethyl-2-bromo-4-nitrobenzene. PROPERTIES: 1,3-dimethyl-2-bromo-4-nitrobenzene is a brominated and nitrated aromatic compound with molecular formula C8H7BrNO2. It typically exists as a colorless to pale yellow crystalline solid with a melting point of approximately 48-52 C. The compound has low water solubility but dissolves in organic solvents like chloroform or acetone. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing toxic bromine vapors and nitrogen oxides. Proper storage involves keeping it in tightly sealed containers below 25 C, away from heat sources and incompatible materials. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating functionalized aromatic systems. The bromo substituent enables cross-coupling reactions to form biaryl structures, while the nitro group provides a handle for reduction to form amines (Tetrahedron Letters). In pharmaceutical research, 1,3-dimethyl-2-bromo-4-nitrobenzene contributes to the development of antimicrobial agents where the brominated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The methyl groups offer steric effects that can influence biological activity and selectivity of derived compounds (European Journal of Medicinal Chemistry).
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