tert-Butyl (trans-4-(4-(trifluoromethyl)phenyl)pyrrolidin-3-yl)carbamate
$250.00
CAS No.: 1212404-61-9
Catalog No.: 192989
Purity: 95%
MF: C16H21F3N2O2
MW: 330.35
Storage: 2-8 degree Celsius
SMILES: FC(C1=CC=C(C=C1)[C@H]1[C@@H](CNC1)NC(OC(C)(C)C)=O)(F)F
Catalog No.: 192989
Purity: 95%
MF: C16H21F3N2O2
MW: 330.35
Storage: 2-8 degree Celsius
SMILES: FC(C1=CC=C(C=C1)[C@H]1[C@@H](CNC1)NC(OC(C)(C)C)=O)(F)F
tert-Butyl (trans-4-(4-(trifluoromethyl)phenyl)pyrrolidin-3-yl)carbamate; CAS No.: 1212404-61-9; tert-Butyl (trans-4-(4-(trifluoromethyl)phenyl)pyrrolidin-3-yl)carbamate. PROPERTIES: This compound presents as a white crystalline powder with molecular formula C14H17F3N2O2 and a molecular weight of 306.30 g/mol. It demonstrates a melting point in the range of 138-142 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as tert-Butyl (trans-4-(4-(trifluoromethyl)phenyl)pyrrolidin-3-yl)carbamate may cause skin irritation. The carbamate group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, tert-Butyl (trans-4-(4-(trifluoromethyl)phenyl)pyrrolidin-3-yl)carbamate serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrrolidine derivatives. Its trifluoromethyl substituent enables improved metabolic stability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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