(2R,4S)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
$250.00
CAS No.: 132622-78-7
Catalog No.: 192991
Purity: 95%
MF: C10H18N2O4
MW: 230.264
Storage: 2-8 degree Celsius
SMILES: N[C@H]1C[C@@H](N(C1)C(=O)OC(C)(C)C)C(=O)O
Catalog No.: 192991
Purity: 95%
MF: C10H18N2O4
MW: 230.264
Storage: 2-8 degree Celsius
SMILES: N[C@H]1C[C@@H](N(C1)C(=O)OC(C)(C)C)C(=O)O
(2R,4S)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid; CAS No.: 132622-78-7; (2R,4S)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C11H18N2O4 and a molecular weight of 238.28 g/mol. It exhibits a melting point in the range of 152-156 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to acidic hydrolysis and should be stored in neutral conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (2R,4S)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid may release irritating vapors upon heating. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (2R,4S)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid serves as a key intermediate for synthesizing cardiovascular agents, as documented in pharmaceutical research focusing on beta-blockers. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic studies have explored its potential in asymmetric catalysis for enantioselective synthesis, as reported in organic chemistry journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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