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tert-butyl 4-(2-ethoxy-2-oxoethyl)-3,3-difluoropiperidine-1-carboxylate; CAS No.: 1334412-95-1; ChemShuttle's expertise in Small molecules synthesis is demonstrated through tert-butyl 4-(2-ethoxy-2-oxoethyl)-3,3-difluoropiperidine-1-carboxylate. This difluorinated ketoester serves as a key intermediate for fluorinated diketone synthesis. The ethoxy group allows controlled hydrolysis to the carboxylic acid, while the difluoro substitution directs enolate formation. Applications include -ketoacid-based protease inhibitors and fluorinated -diketonate metal complexes. The company provides technical guidance on regioselective alkylation reactions using this substrate. Stability studies confirm resistance to retro-aldol decomposition under basic conditions.