tert-butyl 3-phenylpyrrolidine-1-carboxylate
$200.00
CAS No.: 147410-43-3
Catalog No.: 192995
Purity: 95%
MF: C15H21NO2
MW: 247.338
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1CN(CC1)C(=O)OC(C)(C)C
Catalog No.: 192995
Purity: 95%
MF: C15H21NO2
MW: 247.338
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1CN(CC1)C(=O)OC(C)(C)C
tert-butyl 3-phenylpyrrolidine-1-carboxylate; CAS No.: 147410-43-3; tert-butyl 3-phenylpyrrolidine-1-carboxylate. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C14H19NO2 and a molecular weight of 233.31 g/mol. It exhibits a melting point in the range of 138-142 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as tert-butyl 3-phenylpyrrolidine-1-carboxylate may cause skin irritation. The ester group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, tert-butyl 3-phenylpyrrolidine-1-carboxylate serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its phenyl substituent enables improved lipophilicity for enhanced membrane permeability. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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